In this lesson you will learn about how many metabolic pathways are connected to Glycolysis and the Citric Acid Cycle. You will also learn about the allosteric regulation of key enzymes in Glycolysis and Pyruvate oxidation via a feedback inhibition mechanism.
By the end of this lesson, students should be able to
- describe how the metabolism of proteins and fatty acids connects to glycolysis and the Krebs cycle.
- identify the points of entry of metabolites from the breakdown of proteins and lipids/fats into glycolysis and the Krebs cycle
- explain B-oxidation of fatty acids in your own words and identify the end products that would enter glycolysis or the Krebs cycle.
- explain how living cells regulate the amount of energy they produce via a feedback inhibition mechanism
- identify the key enzymes in glycolysis and pyruvate oxidation that are allosterically inhibit or activated by end products such as ATP levels, ADP levels, citrate concentration and NADH.
Let’s begin by examining the connectivity between glycolysis and the citric acid cycle with the metabolism of proteins and fats
In order to build on your vocabulary, please complete the Crossword Puzzle on Cellular Respiration below. Feel free to use a textbook and your own notes from previous video lessons.